Ensuring data integrity is paramount in pharmacovigilance to uphold the reliability and credibility of safety information. Best practices include implementing validated data management systems, conducting regular audits, and maintaining comprehensive documentation. Data anonymization and encryption protect patient privacy, while standardized processes for data entry and validation minimize errors. Continuous training on data integrity principles and adherence to regulatory guidelines further strengthen the foundation for robust pharmacovigilance practices, fostering trust and confidence in drug safety assessments.